KLOW Peptide Blend: Composition, Components and Specifications

Blend overview

KLOW is a defined four-component research blend supplied as one lyophilized powder in a sealed glass vial. Its stated total content is 80 mg: GHK-Cu 50 mg, BPC-157 10 mg, TB-500 10 mg, and KPV 10 mg. The component quantities add to the declared 80 mg total. Naming each component and amount makes the blend specification more informative than a blend name alone.

A blend is a formulation containing multiple separately identified constituents. The label quantity describes the specified component amounts in the vial, not a single compound with one molecular formula or molecular weight. Analytical interpretation should therefore consider each constituent and any method limitations that arise when several compounds are assessed in the same sample.

Component inventory

GHK-Cu is specified as Gly-His-Lys·Cu(II), also known as GHK copper, copper tripeptide-1, or copper peptide. Its stated formula is C14H24N6O4Cu and its approximate molecular weight is 403.9 g/mol. The copper complex contributes 50 mg to the KLOW specification. As a coordinated metal complex, it should be identified with the copper association rather than only by the three-residue ligand name.

BPC-157 is the 15-residue sequence Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val. Its stated formula is C62H98N16O22 and molecular weight is 1419.5 g/mol; the listed CAS number is 137525-51-0. The KLOW specification includes 10 mg of BPC-157. Sequence order and residue identity are essential identifiers and should be reproduced consistently across technical records.

TB-500 is specified here as the Ac-LKKTETQ fragment, with formula C38H68N10O14 and molecular weight 889.0 g/mol. The abbreviation Ac indicates an acetyl group at the sequence’s N-terminus in this nomenclature. The KLOW blend contains 10 mg of this component. KPV denotes the tripeptide Lys-Pro-Val and is specified at 10 mg.

Quantities and identity conventions

The stated 80 mg total follows directly from the four component quantities: 50 mg plus 10 mg plus 10 mg plus 10 mg. This arithmetic is a useful label check. It does not establish measured purity or peptide content, which are separate analytical attributes. A certificate may report component identity, chromatographic results, or content using distinct methods and units.

For a multi-component material, nomenclature should keep component names and quantities unambiguous. GHK-Cu is not interchangeable with uncomplexed GHK; TB-500 is identified as the Ac-LKKTETQ fragment; and KPV should be expanded as Lys-Pro-Val where space allows. Consistency between vial label, product record, and lot documentation reduces ambiguity in inventory and analytical workflows.

Analytical approach for a blend

HPLC can separate constituents when the method provides sufficient resolution. A chromatogram should be interpreted with its method conditions, detector response, integration rules, and reference materials in view. Different compounds can produce different detector responses, so a peak-area percentage for a mixed sample is not automatically a mass percentage for each ingredient.

LC-MS can support assignment of mass signals to expected component identities. MALDI can provide complementary mass information, while amino-acid analysis can examine residue composition. A mixed sample may produce overlapping or complex signals; the report should explain how peaks or ions were assigned and whether components were evaluated individually or as a combined sample. Copper-containing GHK-Cu may require attention to metal-associated ion forms.

Peptide content, identity, and chromatographic profile are distinct reporting categories. A method suitable for detecting a component may not quantify it accurately without suitable calibration and validation. Review stated units, sample basis, reference standards, and any reported uncertainty. A clear COA describes which measurements apply to the blend as a whole and which apply to an individual component.

Lyophilized vial format

KLOW is supplied as lyophilized powder in a sealed glass vial. Lyophilized material is a dry solid produced through freeze-drying. The sealed container limits exposure during storage and transport, while the glass vial provides the specified primary container. The declared component amounts describe the supplied blend; they are not instructions for handling beyond the stated storage and packaging information.

Record the product name, lot code, and receipt date when adding a vial to an inventory. Avoid relying on vial color, powder appearance, or package graphics to establish identity. Those observations do not replace the written specification or lot-matched analytical documentation.

COA and traceability

The certificate of analysis should be matched to the vial’s lot identifier. Check the product and lot fields, analytical methods, reported values, units, and dates. If a result is listed as a percentage, determine whether it represents chromatographic area, measured content, or another defined quantity. Method context is necessary for meaningful comparison between records.

NF7 provides a lot-matched COA that can be verified on the site’s Verify a lot page. Keep the COA with inventory documentation and note the vial lot in any laboratory record referencing the material. This straightforward link preserves traceability from product receipt through later document review.

Storage and dispatch

Store the sealed lyophilized vial at 2–8 °C, protected from light and moisture. Maintain a dry environment and keep the container closed. If a cold sealed vial is moved to a warmer space, let it equilibrate while still sealed before opening the outer packaging; this helps limit condensation on the container. Do not expose the powder to unnecessary humidity.

KLOW ships to addresses within the United States in cold-chain packaging. Check the package at receipt, note any shipping observations, and transfer the sealed vial to the stated storage range. Shipment records, vial labeling, and the lot-matched COA serve different documentation purposes and together support a coherent chain of material identification.

Receiving and recording a KLOW vial

Because KLOW contains four named components, intake records should list each one separately rather than storing the blend name alone. A practical entry captures the product title, the 80 mg total amount, the four component amounts, the lot number from the label and the date the sealed vial was received in cold-chain packaging.

Retrieve the lot-matched Certificate of Analysis from the Verify a lot page and file it with that entry. Check that the COA names GHK-Cu, BPC-157, TB-500 and KPV, that the lot number matches the label exactly and that the analytical sections are complete, then store the sealed vial at 2–8 °C, protected from light and moisture.